| 9. Jornada | 05.03.2016 | River Plate | - | Club Rubio Ñu | 1:4 |  |
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| 10. Jornada | 11.03.2016 | General Díaz | - | River Plate | 3:0 | ||||
| 11. Jornada | 21.03.2016 | River Plate | - | Club Olimpia | 0:3 | ||||
| 12. Jornada | 01.04.2016 | Cerro Porteño | - | River Plate | 4:0 | ||||
| 18. Jornada | 01.05.2016 | Guaraní | - | River Plate | 4:2 | ||||
| 19. Jornada | 06.05.2016 | River Plate | - | Deportivo Capiatá | 1:1 | ||||
| 20. Jornada | 08.05.2016 | Club Rubio Ñu | - | River Plate | 1:2 |
Paraguay