| 1. Jornada | 17.10.2020 | Sol de América | - | Guaraní | 1:0 | ||||
| 3. Jornada | 01.11.2020 | River Plate | - | Guaraní | 1:0 | ||||
| 4. Jornada | 07.11.2020 | Guaraní | - | General Díaz | 2:0 | ||||
| 5. Jornada | 12.11.2020 | Club Nacional | - | Guaraní | 0:0 | ||||
| 6. Jornada | 17.11.2020 | Guaraní | - | San Lorenzo | 2:1 |  |
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| 7. Jornada | 21.11.2020 | 12 de Octubre de Itauguá | - | Guaraní | 1:0 | ||||
| 9. Jornada | 07.12.2020 | Guaraní | - | Club Olimpia | 2:0 |  |
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| 10. Jornada | 12.12.2020 | Libertad | - | Guaraní | 1:1 | ||||
| 11. Jornada | 19.12.2020 | Guaraní | - | Guaireña FC | 1:0 |
Paraguay