| 1. Jornada | 03.07.2022 | Deportivo Guadalajara | - | FC Juárez | 0:0 | ||||
| 3. Jornada | 17.07.2022 | Santos Laguna | - | Deportivo Guadalajara | 1:1 | ||||
| 4. Jornada | 21.07.2022 | Deportivo Guadalajara | - | Club León | 0:0 | ||||
| 5. Jornada | 28.07.2022 | Gallos Blancos | - | Deportivo Guadalajara | 2:2 | ||||
| 6. Jornada | 31.07.2022 | Deportivo Guadalajara | - | CF Pachuca | 0:0 | ||||
| 7. Jornada | 06.08.2022 | Mazatlán FC | - | Deportivo Guadalajara | 2:1 |  |
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| 10. Jornada | 20.08.2022 | Club Necaxa | - | Deportivo Guadalajara | 0:4 | ||||
| 16. Jornada | 24.08.2022 | Deportivo Guadalajara | - | CF Monterrey | 1:0 | ||||
| 12. Jornada | 05.09.2022 | Deportivo Toluca | - | Deportivo Guadalajara | 0:0 |  |
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| 13. Jornada | 08.09.2022 | Club Tijuana | - | Deportivo Guadalajara | 1:2 | ||||
| 14. Jornada | 11.09.2022 | Deportivo Guadalajara | - | Puebla FC | 1:0 |
México