| 1. Jornada | 13.01.2021 | Club Celaya | - | Tepatitlán | 1:1 | ||||
| 2. Jornada | 21.01.2021 | Club Celaya | - | Pumas Tabasco | 2:1 | ||||
| 3. Jornada | 27.01.2021 | Cimarrones de Sonora | - | Club Celaya | 2:2 |  |
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| 4. Jornada | 04.02.2021 | Club Celaya | - | Mineros de Zacatecas | 2:0 | ||||
| 5. Jornada | 15.02.2021 | Atlante | - | Club Celaya | 0:0 | ||||
| 6. Jornada | 18.02.2021 | Club Celaya | - | Cancún FC | 4:0 | ||||
| 7. Jornada | 28.02.2021 | Atlético Morelia | - | Club Celaya | 0:2 | |
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| 8. Jornada | 06.03.2021 | Club Celaya | - | Coyotes de Tlaxcala | 0:0 | ||||
| 9. Jornada | 11.03.2021 | TM Fútbol Club | - | Club Celaya | 1:0 | |
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| 10. Jornada | 18.03.2021 | Club Celaya | - | Dorados de Sinaloa | 2:2 | ||||
| 11. Jornada | 24.03.2021 | Venados FC | - | Club Celaya | 0:1 | ||||
| 12. Jornada | 27.03.2021 | Club Celaya | - | Alebrijes de Oaxaca | 0:0 | |
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| 13. Jornada | 02.04.2021 | Leones Negros | - | Club Celaya | 3:1 | ||||
| 14. Jornada | 07.04.2021 | Correcaminos UAT | - | Club Celaya | 1:2 | ||||
| 15. Jornada | 16.04.2021 | Club Celaya | - | Tapatío | 0:0 |
México