| 1. Jornada | 09.01.2021 | UANL Tigres [Sub 20] | - | Club León [Sub 20] | 6:0 | ||||
| 5. Jornada | 08.02.2021 | Club León [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 3:0 | ||||
| 6. Jornada | 13.02.2021 | Club Tijuana [Sub 20] | - | Club León [Sub 20] | 1:1 | ||||
| 9. Jornada | 02.03.2021 | Club León [Sub 20] | - | Puebla FC [Sub 20] | 2:1 | ||||
| 3. Jornada | 10.03.2021 | CF Monterrey [Sub 20] | - | Club León [Sub 20] | 0:0 | ||||
| 11. Jornada | 15.03.2021 | Club León [Sub 20] | - | Club Necaxa [Sub 20] | 2:1 | ||||
| 12. Jornada | 21.03.2021 | Santos Laguna [Sub 20] | - | Club León [Sub 20] | 3:0 | ||||
| 13. Jornada | 04.04.2021 | Club León [Sub 20] | - | Deportivo Toluca [Sub 20] | 0:4 | ||||
| 16. Jornada | 23.04.2021 | Mazatlán FC [Sub 20] | - | Club León [Sub 20] | 1:3 |
México