| 1. Jornada | 13.07.2005 | Volyn Lutsk | - | Shakhtar Donetsk | 0:1 | ||||
| 5. Jornada | 06.08.2005 | Tavriya Simferopol (1958-2014) | - | Shakhtar Donetsk | 0:3 | ||||
| 6. Jornada | 20.08.2005 | Metalist Kharkiv | - | Shakhtar Donetsk | 1:5 |  |
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| 7. Jornada | 28.08.2005 | Shakhtar Donetsk | - | Metalurg Zaporizhya | 3:1 | ||||
| 8. Jornada | 11.09.2005 | Arsenal Kiev | - | Shakhtar Donetsk | 0:0 | |
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| 9. Jornada | 18.09.2005 | Shakhtar Donetsk | - | Stal Alchevsk | 1:1 | ||||
| 11. Jornada | 03.10.2005 | Shakhtar Donetsk | - | FK Illichivets | 6:0 | ||||
| 12. Jornada | 16.10.2005 | Vorskla Poltava | - | Shakhtar Donetsk | 0:2 | |
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| 18. Jornada | 05.12.2005 | Shakhtar Donetsk | - | FK Kharkiv | 3:0 | |
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| 20. Jornada | 05.03.2006 | Shakhtar Donetsk | - | Tavriya Simferopol (1958-2014) | 1:1 |  |
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| 25. Jornada | 09.04.2006 | Shakhtar Donetsk | - | Zakarpattya Uzhgorod | 3:0 | |
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| 27. Jornada | 21.04.2006 | Shakhtar Donetsk | - | Vorskla Poltava | 0:0 |
Rumania