| 1. Jornada | 22.08.2020 | Sepsi OSK | - | CS Universitatea Craiova | 0:1 | ||||
| 2. Jornada | 29.08.2020 | CFR Cluj | - | Sepsi OSK | 0:0 | ||||
| 3. Jornada | 13.09.2020 | Astra Giurgiu | - | Sepsi OSK | 2:2 | ||||
| 4. Jornada | 19.09.2020 | Sepsi OSK | - | FC Viitorul Constanța | 1:1 |  |
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| 5. Jornada | 25.09.2020 | FC Voluntari | - | Sepsi OSK | 1:2 | ||||
| 8. Jornada | 24.10.2020 | Sepsi OSK | - | Dinamo Bucureşti | 2:0 | ||||
| 10. Jornada | 07.11.2020 | Sepsi OSK | - | FC Hermannstadt | 1:1 | ||||
| 11. Jornada | 23.11.2020 | Chindia Târgoviște | - | Sepsi OSK | 1:2 | |
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| 12. Jornada | 05.12.2020 | Sepsi OSK | - | FC Botoşani | 2:2 | |
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| 13. Jornada | 12.12.2020 | Gaz Metan Mediaş | - | Sepsi OSK | 0:3 | |
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| 15. Jornada | 21.12.2020 | FCSB | - | Sepsi OSK | 1:1 | ||||
| 16. Jornada | 12.01.2021 | CS Universitatea Craiova | - | Sepsi OSK | 0:0 | ||||
| 17. Jornada | 17.01.2021 | Sepsi OSK | - | CFR Cluj | 0:1 | ||||
| 27. Jornada | 15.03.2021 | FC Botoşani | - | Sepsi OSK | 1:2 | ||||
| 28. Jornada | 21.03.2021 | Sepsi OSK | - | Gaz Metan Mediaş | 1:1 | ||||
| 29. Jornada | 04.04.2021 | UTA Arad | - | Sepsi OSK | 2:0 |
Rumania