| 1. Jornada | 10.01.2016 | CF América | - | Puebla FC | 0:0 |  |
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| 2. Jornada | 18.01.2016 | Puebla FC | - | CF Monterrey | 1:3 | ||||
| 3. Jornada | 24.01.2016 | Pumas UNAM | - | Puebla FC | 0:1 | ||||
| 4. Jornada | 31.01.2016 | Deportivo Toluca | - | Puebla FC | 1:1 | |
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| 7. Jornada | 22.02.2016 | Puebla FC | - | Dorados de Sinaloa | 3:2 | ||||
| 8. Jornada | 28.02.2016 | Santos Laguna | - | Puebla FC | 1:1 |  |
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| 15. Jornada | 25.04.2016 | Puebla FC | - | Chiapas FC | 2:1 | ||||
| 16. Jornada | 30.04.2016 | Club Tijuana | - | Puebla FC | 0:0 | ||||
| 17. Jornada | 09.05.2016 | Puebla FC | - | Gallos Blancos | 3:1 |
México