| 2. Jornada | 26.01.2019 | Club Nacional | - | Guaraní | 0:2 | ||||
| 1. Jornada | 14.02.2019 | Club Nacional | - | Club Olimpia | 2:4 | ||||
| 6. Jornada | 19.02.2019 | Club Nacional | - | Sol de América | 0:1 | ||||
| 7. Jornada | 23.02.2019 | Cerro Porteño | - | Club Nacional | 1:1 | ||||
| 9. Jornada | 03.03.2019 | Deportivo Capiatá | - | Club Nacional | 1:0 | ||||
| 10. Jornada | 11.03.2019 | Club Nacional | - | General Díaz | 1:0 | ||||
| 11. Jornada | 16.03.2019 | River Plate | - | Club Nacional | 1:1 | ||||
| 12. Jornada | 25.03.2019 | Club Olimpia | - | Club Nacional | 0:0 | ||||
| 8. Jornada | 28.03.2019 | Club Nacional | - | Libertad | 0:1 | ||||
| 13. Jornada | 31.03.2019 | Guaraní | - | Club Nacional | 2:2 | ||||
| 14. Jornada | 05.04.2019 | Club Nacional | - | San Lorenzo | 3:1 |  |
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| 15. Jornada | 10.04.2019 | Sportivo Luqueño | - | Club Nacional | 1:1 | ||||
| 16. Jornada | 15.04.2019 | Club Nacional | - | Deportivo Santaní | 0:0 | ||||
| 17. Jornada | 22.04.2019 | Sol de América | - | Club Nacional | 3:1 | ||||
| 18. Jornada | 29.04.2019 | Club Nacional | - | Cerro Porteño | 0:3 | ||||
| 19. Jornada | 03.05.2019 | Libertad | - | Club Nacional | 1:2 | ||||
| 21. Jornada | 14.05.2019 | General Díaz | - | Club Nacional | 1:1 |
Argentina