| 2. Jornada | 15.01.2022 | Deportivo Toluca [] | - | Club Necaxa [] | 2:1 | ||||
| 3. Jornada | 22.01.2022 | Gallos Blancos [] | - | Deportivo Toluca [] | 1:1 | ||||
| 6. Jornada | 12.02.2022 | Puebla FC [] | - | Deportivo Toluca [] | 0:4 | ||||
| 1. Jornada | 15.02.2022 | FC Juárez [] | - | Deportivo Toluca [] | 2:0 | ||||
| 8. Jornada | 26.02.2022 | CF América [] | - | Deportivo Toluca [] | 1:2 |
México