| 2. Jornada | 04.08.2000 | Huracán | - | Rosario Central | 3:1 |  |
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| 1. Jornada | 13.08.2000 | Rosario Central | - | Almagro | 1:1 | ||||
| 3. Jornada | 20.08.2000 | Rosario Central | - | CA Lanús | 1:1 | ||||
| 4. Jornada | 27.08.2000 | River Plate | - | Rosario Central | 4:1 | ||||
| 5. Jornada | 06.09.2000 | Rosario Central | - | Vélez Sarsfield | 2:2 | ||||
| 7. Jornada | 17.09.2000 | Rosario Central | - | Estudiantes | 2:3 | ||||
| 8. Jornada | 23.09.2000 | Rosario Central | - | Independiente | 1:1 | |
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| 9. Jornada | 01.10.2000 | Talleres de Córdoba | - | Rosario Central | 2:0 | ||||
| 13. Jornada | 05.11.2000 | Boca Juniors | - | Rosario Central | 3:3 | ||||
| 16. Jornada | 26.11.2000 | Rosario Central | - | Gimnasia de La Plata | 2:0 | |
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| 17. Jornada | 03.12.2000 | Newell's Old Boys | - | Rosario Central | 0:0 | |
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| 19. Jornada | 16.12.2000 | Belgrano | - | Rosario Central | 1:4 |
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