| 4. Jornada | 29.01.2022 | CF Pachuca [Sub 16] | - | CF América [Sub 16] | 0:3 | ||||
| 6. Jornada | 12.02.2022 | Club Necaxa [Sub 16] | - | CF Pachuca [Sub 16] | 2:2 | ||||
| 13. Jornada | 03.04.2022 | FC Juárez [Sub 16] | - | CF Pachuca [Sub 16] | 1:2 | ||||
| 14. Jornada | 09.04.2022 | CF Pachuca [Sub 16] | - | Club Necaxa [Sub 16] | 1:2 | ||||
| 18. Jornada | 07.05.2022 | Gallos Blancos [Sub 16] | - | CF Pachuca [Sub 16] | 2:2 |
México