| 1. Jornada | 16.05.2021 | Deportivo Maldonado | - | Liverpool | 2:4 | ||||
| 2. Jornada | 24.05.2021 | River Plate | - | Liverpool | 3:2 | ||||
| 3. Jornada | 29.05.2021 | Liverpool | - | Cerro Largo | 3:0 | ||||
| 4. Jornada | 04.06.2021 | Progreso | - | Liverpool | 1:3 | ||||
| 6. Jornada | 17.06.2021 | Plaza Colonia | - | Liverpool | 2:1 | ||||
| 7. Jornada | 22.06.2021 | Liverpool | - | Fénix | 5:2 | ||||
| 8. Jornada | 27.06.2021 | Boston River | - | Liverpool | 1:1 | ||||
| 9. Jornada | 06.07.2021 | Liverpool | - | Montevideo Wanderers | 2:1 |  |
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| 10. Jornada | 12.07.2021 | Rentistas | - | Liverpool | 2:1 | ||||
| 11. Jornada | 25.07.2021 | Liverpool | - | Peñarol | 3:3 | ||||
| 12. Jornada | 01.08.2021 | Montevideo City Torque | - | Liverpool | 0:3 |
Uruguay