| 1. Jornada | 01.08.2022 | Liverpool | - | Defensor Sporting | 1:3 |  |
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| 2. Jornada | 08.08.2022 | Albion | - | Liverpool | 1:1 | ||||
| 3. Jornada | 14.08.2022 | Liverpool | - | Nacional | 0:1 | ||||
| 6. Jornada | 20.08.2022 | Rentistas | - | Liverpool | 0:2 | ||||
| 5. Jornada | 28.08.2022 | Liverpool | - | Deportivo Maldonado | 1:1 | ||||
| 7. Jornada | 09.09.2022 | Liverpool | - | Cerrito | 3:0 | ||||
| 10. Jornada | 24.09.2022 | Liverpool | - | Montevideo Wanderers | 1:1 | ||||
| 11. Jornada | 01.10.2022 | Plaza Colonia | - | Liverpool | 1:3 | ||||
| 12. Jornada | 09.10.2022 | Liverpool | - | Boston River | 3:2 |  |
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| 13. Jornada | 13.10.2022 | River Plate | - | Liverpool | 0:1 | |
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| 14. Jornada | 16.10.2022 | Liverpool | - | Cerro Largo | 1:0 | |
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| 15. Jornada | 23.10.2022 | Fénix | - | Liverpool | 0:3 |
Uruguay