| 1. Jornada | 23.07.2021 | Club Necaxa [Sub 18] | - | Santos Laguna [Sub 18] | 3:1 |  |
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| 2. Jornada | 31.07.2021 | CF América [Sub 18] | - | Club Necaxa [Sub 18] | 2:3 | ||||
| 3. Jornada | 06.08.2021 | Club Necaxa [Sub 18] | - | Cruz Azul [Sub 18] | 5:0 | ||||
| 16. Jornada | 29.10.2021 | Club Necaxa [Sub 18] | - | Mazatlán FC [Sub 18] | 3:0 | ||||
| 17. Jornada | 06.11.2021 | Club León [Sub 18] | - | Club Necaxa [Sub 18] | 3:2 |
México