| 4. Jornada | 22.06.2022 | Central Córdoba SdE | - | San Lorenzo | 0:2 | ||||
| 5. Jornada | 26.06.2022 | San Lorenzo | - | Tigre | 1:1 | ||||
| 6. Jornada | 03.07.2022 | Barracas Central | - | San Lorenzo | 2:1 |  |
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| 11. Jornada | 30.07.2022 | Argentinos Juniors | - | San Lorenzo | 0:1 | ||||
| 13. Jornada | 13.08.2022 | Patronato de Paraná | - | San Lorenzo | 3:2 | ||||
| 15. Jornada | 23.08.2022 | Racing Club | - | San Lorenzo | 1:2 | ||||
| 17. Jornada | 06.09.2022 | Defensa y Justicia | - | San Lorenzo | 0:0 | ||||
| 25. Jornada | 12.10.2022 | Gimnasia de La Plata | - | San Lorenzo | 0:1 | ||||
| 26. Jornada | 18.10.2022 | Sarmiento de Junín | - | San Lorenzo | 2:4 | ||||
| 27. Jornada | 22.10.2022 | San Lorenzo | - | Aldosivi | 3:0 |
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