| 1. Jornada | 24.07.2022 | RSC Anderlecht | - | KV Oostende | 2:0 | ||||
| 2. Jornada | 30.07.2022 | Cercle Brugge | - | RSC Anderlecht | 1:0 | ||||
| 3. Jornada | 07.08.2022 | RSC Anderlecht | - | RFC Seraing | 3:1 | ||||
| 4. Jornada | 14.08.2022 | Sint-Truidense VV | - | RSC Anderlecht | 0:3 |  |
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| 6. Jornada | 28.08.2022 | Union Saint-Gilloise | - | RSC Anderlecht | 2:1 | ||||
| 5. Jornada | 01.09.2022 | RSC Anderlecht | - | Gante | 0:1 | ||||
| 7. Jornada | 04.09.2022 | RSC Anderlecht | - | Oud-Heverlee Leuven | 2:2 | ||||
| 8. Jornada | 11.09.2022 | KVC Westerlo | - | RSC Anderlecht | 2:1 | ||||
| 9. Jornada | 18.09.2022 | RSC Anderlecht | - | KV Kortrijk | 4:1 | ||||
| 11. Jornada | 09.10.2022 | KV Mechelen | - | RSC Anderlecht | 1:3 | ||||
| 16. Jornada | 06.11.2022 | Royal Antwerp FC | - | RSC Anderlecht | 0:0 | ||||
| 17. Jornada | 13.11.2022 | RSC Anderlecht | - | KRC Genk | 0:2 | ||||
| 18. Jornada | 26.12.2022 | Sporting Charleroi | - | RSC Anderlecht | 0:1 | ||||
| 31. Jornada | 02.04.2023 | KAS Eupen | - | RSC Anderlecht | 0:1 | ||||
| 33. Jornada | 16.04.2023 | KRC Genk | - | RSC Anderlecht | 5:2 | ||||
| 34. Jornada | 23.04.2023 | RSC Anderlecht | - | KV Mechelen | 2:3 |
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