| 4. Jornada | 14.08.2021 | Pumas UNAM [Sub 20] | - | Gallos Blancos [Sub 20] | 1:4 | ||||
| 5. Jornada | 17.08.2021 | Club Necaxa [Sub 20] | - | Pumas UNAM [Sub 20] | 1:1 | ||||
| 6. Jornada | 22.08.2021 | Pumas UNAM [Sub 20] | - | Puebla FC [Sub 20] | 1:3 | ||||
| 7. Jornada | 29.08.2021 | Deportivo Toluca [Sub 20] | - | Pumas UNAM [Sub 20] | 2:2 | ||||
| 8. Jornada | 12.09.2021 | Pumas UNAM [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 1:2 |
México