| 1. Jornada | 25.07.2010 | The Strongest | - | Club Aurora | 4:2 |  |
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| 5. Jornada | 22.08.2010 | The Strongest | - | Universitario de Sucre | 3:0 |  |
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| 6. Jornada | 30.08.2010 | Blooming | - | The Strongest | 2:1 | ||||
| 7. Jornada | 04.09.2010 | The Strongest | - | Jorge Wilstermann | 2:1 | ||||
| 8. Jornada | 09.09.2010 | The Strongest | - | La Paz FC | 1:3 | ||||
| 10. Jornada | 19.09.2010 | The Strongest | - | Real Potosí | 4:2 |  |
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| 11. Jornada | 27.09.2010 | Oriente Petrolero | - | The Strongest | 4:0 | |
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| 13. Jornada | 14.10.2010 | The Strongest | - | Bolívar | 3:2 | ||||
| 15. Jornada | 17.10.2010 | The Strongest | - | Club San José | 1:2 | |
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| 16. Jornada | 24.10.2010 | Universitario de Sucre | - | The Strongest | 1:0 | ||||
| 18. Jornada | 31.10.2010 | Jorge Wilstermann | - | The Strongest | 3:1 | |
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| 17. Jornada | 04.11.2010 | The Strongest | - | Blooming | 2:1 | |
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| 20. Jornada | 14.11.2010 | The Strongest | - | CD Guabirá | 1:0 | ||||
| 21. Jornada | 21.11.2010 | Real Potosí | - | The Strongest | 2:3 | ||||
| 22. Jornada | 28.11.2010 | The Strongest | - | Oriente Petrolero | 1:1 |
Bolivia