| 4. Jornada | 28.08.2021 | FC Sion II | - | FC Stade Nyonnais | 1:1 | ||||
| 5. Jornada | 04.09.2021 | AC Bellinzona | - | FC Sion II | 3:1 | ||||
| 6. Jornada | 11.09.2021 | FC Sion II | - | BSC Young Boys II | 2:0 | ||||
| 8. Jornada | 25.09.2021 | FC Sion II | - | FC Biel/Bienne | 1:2 |  |
|||
| 7. Jornada | 29.09.2021 | FC Chiasso | - | FC Sion II | 1:2 | ||||
| 9. Jornada | 02.10.2021 | FC Basel 1893 II | - | FC Sion II | 6:2 | ||||
| 10. Jornada | 10.10.2021 | FC Rapperswil-Jona | - | FC Sion II | 2:0 | ||||
| 15. Jornada | 13.11.2021 | FC Sion II | - | SC YF/Juventus Zürich | 1:3 | ||||
| 16. Jornada | 20.11.2021 | FC Sion II | - | SC Cham | 3:4 | ||||
| 17. Jornada | 27.11.2021 | FC Black Stars Basel | - | FC Sion II | 2:2 | |
|||
| 22. Jornada | 12.03.2022 | FC Sion II | - | FC Chiasso | 0:1 | |
|||
| 24. Jornada | 26.03.2022 | FC Sion II | - | FC Basel 1893 II | 1:2 | |
|||
| 25. Jornada | 02.04.2022 | FC Sion II | - | FC Rapperswil-Jona | 0:2 | ||||
| 26. Jornada | 06.04.2022 | Etoile Carouge FC | - | FC Sion II | 4:1 |
Suiza