| 12. Jornada | 17.09.2021 | Rosario Central II | - | San Lorenzo II | 1:2 | ||||
| 18. Jornada | 24.10.2021 | Rosario Central II | - | Racing Club II | 1:2 | ||||
| 20. Jornada | 05.11.2021 | Defensa y Justicia II | - | Rosario Central II | 1:2 | ||||
| 21. Jornada | 20.11.2021 | Rosario Central II | - | Atlético Tucumán II | 4:1 |  |
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| 22. Jornada | 24.11.2021 | Colón de Santa Fe II | - | Rosario Central II | 1:1 | ||||
| 23. Jornada | 28.11.2021 | Rosario Central II | - | River Plate II | 2:0 | ||||
| 24. Jornada | 03.12.2021 | Lanús II | - | Rosario Central II | 2:3 | |
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| 25. Jornada | 10.12.2021 | Rosario Central II | - | Huracán II | 2:0 |
Argentina