| 1. Jornada | 23.08.2021 | Apollon Limassol | - | Ethnikos Achna | 4:2 |  |
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| 3. Jornada | 20.09.2021 | Anorthosis Famagusta | - | Ethnikos Achna | 2:1 | ||||
| 4. Jornada | 24.09.2021 | Doxa Katokopias | - | Ethnikos Achna | 0:0 | ||||
| 5. Jornada | 02.10.2021 | Ethnikos Achna | - | Aris Limassol | 0:3 | ||||
| 7. Jornada | 23.10.2021 | Ethnikos Achna | - | AEL Limassol | 2:2 | ||||
| 8. Jornada | 31.10.2021 | AEK Larnaca | - | Ethnikos Achna | 1:0 | ||||
| 9. Jornada | 07.11.2021 | Ethnikos Achna | - | Omonia Nikosia | 0:2 | |
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| 11. Jornada | 26.11.2021 | Ethnikos Achna | - | Olympiacos Nikosia | 1:0 | ||||
| 12. Jornada | 06.12.2021 | Ethnikos Achna | - | Apollon Limassol | 0:1 | ||||
| 13. Jornada | 11.12.2021 | PAEEK | - | Ethnikos Achna | 0:2 | |
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| 14. Jornada | 18.12.2021 | Ethnikos Achna | - | Anorthosis Famagusta | 0:2 | ||||
| 16. Jornada | 08.01.2022 | Aris Limassol | - | Ethnikos Achna | 2:1 | ||||
| 17. Jornada | 15.01.2022 | Ethnikos Achna | - | APOEL Nikosia | 0:3 | |
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| 18. Jornada | 22.01.2022 | AEL Limassol | - | Ethnikos Achna | 1:0 |
Letonia