| 11. Jornada | 14.03.2021 | Junior Managua | - | ART Municipal Jalapa | 2:1 | ||||
| 12. Jornada | 01.04.2021 | Club Deportivo Ocotal | - | Junior Managua | 2:1 | ||||
| 13. Jornada | 11.04.2021 | Junior Managua | - | CD Walter Ferretti | 1:1 | ||||
| 14. Jornada | 18.04.2021 | Chinandega | - | Junior Managua | 2:1 | ||||
| 15. Jornada | 25.04.2021 | Junior Managua | - | Diriangén FC | 0:1 | ||||
| 16. Jornada | 29.04.2021 | Real Madriz | - | Junior Managua | 1:2 |  |
|||
| 17. Jornada | 02.05.2021 | Junior Managua | - | Real Estelí FC | 0:2 | ||||
| 18. Jornada | 05.05.2021 | Juventus Managua | - | Junior Managua | 2:2 |
Nicaragua