| 1. Jornada | 30.07.2022 | FC Zimbru | - | FC Sheriff | 1:1 | ||||
| 2. Jornada | 06.08.2022 | FC Sfîntul Gheorghe | - | FC Sheriff | 1:3 | ||||
| 3. Jornada | 14.08.2022 | FC Sheriff | - | Dinamo-Auto | 2:0 |  |
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| 4. Jornada | 21.08.2022 | FC Bălţi | - | FC Sheriff | 0:3 | ||||
| 5. Jornada | 29.08.2022 | FC Sheriff | - | CS Petrocub | 1:1 | ||||
| 6. Jornada | 03.09.2022 | Dacia Buiucani | - | FC Sheriff | 0:2 | ||||
| 7. Jornada | 11.09.2022 | FC Sheriff | - | FC Milsami | 2:0 | |
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| 8. Jornada | 18.09.2022 | FC Sheriff | - | FC Zimbru | 0:0 | ||||
| 9. Jornada | 02.10.2022 | FC Sheriff | - | FC Sfîntul Gheorghe | 3:0 | |
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| 10. Jornada | 09.10.2022 | Dinamo-Auto | - | FC Sheriff | 0:1 | ||||
| 11. Jornada | 16.10.2022 | FC Sheriff | - | FC Bălţi | 2:1 | ||||
| 12. Jornada | 23.10.2022 | CS Petrocub | - | FC Sheriff | 1:0 | ||||
| 14. Jornada | 09.11.2022 | FC Milsami | - | FC Sheriff | 0:2 | |
Nigeria