| 16. Jornada | 28.11.2021 | Slavia Praga | - | FK Teplice | 3:0 |  |
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| 17. Jornada | 04.12.2021 | FK Teplice | - | FC Fastav Zlín | 4:1 |  |
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| 18. Jornada | 12.12.2021 | FK Jablonec | - | FK Teplice | 0:2 | |
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| 19. Jornada | 19.12.2021 | FK Teplice | - | FK Mladá Boleslav | 0:1 | |
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| 22. Jornada | 20.02.2022 | FK Teplice | - | MFK Karviná | 1:0 | ||||
| 23. Jornada | 27.02.2022 | Sigma Olomouc | - | FK Teplice | 0:0 | ||||
| 24. Jornada | 06.03.2022 | FK Teplice | - | 1. FC Slovácko | 0:1 |
República Checa