| 1. Jornada | 03.08.2002 | Atlas Guadalajara | - | Santos Laguna | 1:2 |  |
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| 2. Jornada | 11.08.2002 | Santos Laguna | - | Gallos Blancos (old) | 0:0 | ||||
| 3. Jornada | 18.08.2002 | Puebla FC | - | Santos Laguna | 3:1 | |
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| 4. Jornada | 25.08.2002 | Santos Laguna | - | CF América | 0:1 | ||||
| 5. Jornada | 31.08.2002 | Jaguares Chiapas | - | Santos Laguna | 2:0 | ||||
| 6. Jornada | 08.09.2002 | Santos Laguna | - | Cruz Azul | 1:3 | ||||
| 7. Jornada | 12.09.2002 | UAG Tecos | - | Santos Laguna | 2:1 | ||||
| 8. Jornada | 15.09.2002 | Santos Laguna | - | UANL Tigres | 3:1 | |
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| 9. Jornada | 22.09.2002 | CF Pachuca | - | Santos Laguna | 0:0 | ||||
| 10. Jornada | 28.09.2002 | Santos Laguna | - | Deportivo Guadalajara | 4:2 | |
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| 11. Jornada | 05.10.2002 | Real San Luis | - | Santos Laguna | 1:1 | |
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| 12. Jornada | 13.10.2002 | Santos Laguna | - | Atletico Celaya | 2:0 | |
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| 13. Jornada | 17.10.2002 | Santos Laguna | - | Club Necaxa | 3:2 | |
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| 14. Jornada | 20.10.2002 | Atlante | - | Santos Laguna | 3:1 | |
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| 15. Jornada | 27.10.2002 | Santos Laguna | - | Monarcas Morelia | 2:2 | ||||
| 16. Jornada | 03.11.2002 | Pumas UNAM | - | Santos Laguna | 1:0 | ||||
| 17. Jornada | 10.11.2002 | Santos Laguna | - | Veracruz (old) | 4:2 | |
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