| 4. Jornada | 09.10.2021 | Club Tijuana [] | - | Puebla FC [] | 5:0 | ||||
| 7. Jornada | 30.10.2021 | Club Tijuana [] | - | Gallos Blancos [] | 3:0 | ||||
| 8. Jornada | 06.11.2021 | FC Juárez [] | - | Club Tijuana [] | 1:1 | ||||
| 9. Jornada | 13.11.2021 | Pumas UNAM [] | - | Club Tijuana [] | 2:1 | ||||
| 10. Jornada | 20.11.2021 | Club Tijuana [] | - | Cruz Azul [] | 1:2 |  |
México