| 10. Jornada | 22.08.2022 | CF Pachuca | - | Club León | 1:0 | ||||
| 16. Jornada | 26.08.2022 | CF Pachuca | - | Atlas Guadalajara | 3:1 |  |
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| 11. Jornada | 28.08.2022 | Deportivo Toluca | - | CF Pachuca | 1:4 | ||||
| 12. Jornada | 04.09.2022 | CF Pachuca | - | Santos Laguna | 2:0 | |
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| 13. Jornada | 08.09.2022 | Puebla FC | - | CF Pachuca | 2:2 | ||||
| 14. Jornada | 12.09.2022 | CF Pachuca | - | Club Tijuana | 6:1 | ||||
| 8. Jornada | 15.09.2022 | FC Juárez | - | CF Pachuca | 2:1 | ||||
| 15. Jornada | 19.09.2022 | Atlético San Luis | - | CF Pachuca | 1:2 | ||||
| 17. Jornada | 02.10.2022 | CF Monterrey | - | CF Pachuca | 0:0 |
México