| 3. Jornada | 02.05.2010 | Real Salt Lake | - | Toronto FC | 2:1 | ||||
| 3. Jornada | 14.05.2010 | Real Salt Lake | - | Houston Dynamo | 3:1 | ||||
| 3. Jornada | 23.05.2010 | CD Chivas | - | Real Salt Lake | 1:2 |  |
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| 3. Jornada | 30.05.2010 | Real Salt Lake | - | Kansas City Wizards | 4:1 | ||||
| 4. Jornada | 06.06.2010 | D.C. United | - | Real Salt Lake | 0:0 | ||||
| 4. Jornada | 26.06.2010 | Real Salt Lake | - | San Jose Earthquakes | 0:0 | ||||
| 5. Jornada | 03.07.2010 | Real Salt Lake | - | New England Revolution | 5:0 | ||||
| 5. Jornada | 09.07.2010 | Chicago Fire | - | Real Salt Lake | 0:1 | ||||
| 5. Jornada | 18.07.2010 | FC Dallas | - | Real Salt Lake | 2:0 | ||||
| 6. Jornada | 01.08.2010 | Real Salt Lake | - | D.C. United | 3:0 | ||||
| 6. Jornada | 12.08.2010 | Philadelphia Union | - | Real Salt Lake | 1:1 | |
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| 6. Jornada | 29.08.2010 | Toronto FC | - | Real Salt Lake | 0:0 | ||||
| 7. Jornada | 26.09.2010 | Real Salt Lake | - | Colorado Rapids | 1:1 | ||||
| 8. Jornada | 03.10.2010 | New England Revolution | - | Real Salt Lake | 1:2 | ||||
| 8. Jornada | 17.10.2010 | Real Salt Lake | - | FC Dallas | 2:0 |
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