| 4. Jornada | 24.02.2022 | Talleres de Córdoba II | - | Newell's Old Boys II | 2:2 | ||||
| 5. Jornada | 04.03.2022 | Newell's Old Boys II | - | Atlético Tucumán II | 2:3 | ||||
| 10. Jornada | 13.04.2022 | Newell's Old Boys II | - | Patronato de Paraná II | 1:0 | ||||
| 12. Jornada | 26.04.2022 | Racing Club II | - | Newell's Old Boys II | 1:1 |  |
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| 13. Jornada | 30.04.2022 | Newell's Old Boys II | - | San Lorenzo II | 0:3 | ||||
| 14. Jornada | 05.05.2022 | Gimnasia de La Plata II | - | Newell's Old Boys II | 1:3 | |
Argentina