| 1. Jornada | 14.01.2023 | UD Universitario | - | San Francisco FC | 0:1 | ||||
| 2. Jornada | 21.01.2023 | UMECIT | - | San Francisco FC | 1:1 | ||||
| 3. Jornada | 28.01.2023 | San Francisco FC | - | Independiente de La Chorrera | 2:2 | ||||
| 4. Jornada | 04.02.2023 | San Francisco FC | - | Herrera FC | 0:0 |  |
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| 6. Jornada | 15.02.2023 | San Francisco FC | - | Potros del Este | 1:3 | ||||
| 7. Jornada | 25.02.2023 | San Francisco FC | - | Sporting San Miguelito | 1:1 | ||||
| 8. Jornada | 04.03.2023 | San Francisco FC | - | Plaza Amador | 1:1 | ||||
| 9. Jornada | 12.03.2023 | Tauro FC | - | San Francisco FC | 2:0 | ||||
| 10. Jornada | 20.03.2023 | Alianza | - | San Francisco FC | 0:0 |
Panamá