| 5. Jornada | 05.02.2022 | Mazatlán FC [Sub 16] | - | UANL Tigres [Sub 16] | 2:2 | ||||
| 8. Jornada | 26.02.2022 | Mazatlán FC [Sub 16] | - | Santos Laguna [Sub 16] | 2:0 | ||||
| 9. Jornada | 05.03.2022 | Club León [Sub 16] | - | Mazatlán FC [Sub 16] | 4:0 | ||||
| 11. Jornada | 19.03.2022 | UANL Tigres [Sub 16] | - | Mazatlán FC [Sub 16] | 0:0 | ||||
| 12. Jornada | 26.03.2022 | Santos Laguna [Sub 16] | - | Mazatlán FC [Sub 16] | 3:1 | ||||
| 15. Jornada | 16.04.2022 | Atlas Guadalajara [Sub 16] | - | Mazatlán FC [Sub 16] | 5:0 | ||||
| 17. Jornada | 30.04.2022 | Club Tijuana [Sub 16] | - | Mazatlán FC [Sub 16] | 1:2 |  |
México