| 2. Jornada | 31.07.2018 | Leones FC | - | Alianza Petrolera | 0:1 |  |
|||
| 3. Jornada | 07.08.2018 | Jaguares de Córdoba | - | Leones FC | 2:0 | |
|||
| 4. Jornada | 11.08.2018 | Leones FC | - | Atlético Bucaramanga | 0:1 | ||||
| 9. Jornada | 09.09.2018 | Independiente Medellín | - | Leones FC | 1:1 | ||||
| 10. Jornada | 15.09.2018 | Leones FC | - | Deportivo Cali | 0:0 | ||||
| 12. Jornada | 29.09.2018 | Leones FC | - | Atlético Junior | 2:2 | |
|||
| 13. Jornada | 09.10.2018 | Once Caldas | - | Leones FC | 0:0 | ||||
| 14. Jornada | 14.10.2018 | Leones FC | - | La Equidad | 0:1 | |
|||
| 15. Jornada | 19.10.2018 | Millonarios | - | Leones FC | 1:0 | |
|||
| 17. Jornada | 27.10.2018 | Leones FC | - | Santa Fe | 0:2 | ||||
| 18. Jornada | 04.11.2018 | Patriotas FC | - | Leones FC | 2:1 | ||||
| 19. Jornada | 11.11.2018 | Leones FC | - | Atlético Nacional | 2:2 | |
Colombia