| 1. Jornada | 24.07.2021 | FK Pardubice | - | MFK Karviná | 2:2 | ||||
| 3. Jornada | 08.08.2021 | FK Pardubice | - | FK Mladá Boleslav | 1:1 | ||||
| 4. Jornada | 15.08.2021 | Baník Ostrava | - | FK Pardubice | 3:1 | ||||
| 5. Jornada | 21.08.2021 | FK Pardubice | - | Bohemians Praha 1905 | 3:0 | ||||
| 6. Jornada | 28.08.2021 | 1. FC Slovácko | - | FK Pardubice | 2:1 | ||||
| 7. Jornada | 11.09.2021 | FK Pardubice | - | Slovan Liberec | 2:2 |  |
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| 19. Jornada | 18.12.2021 | Bohemians Praha 1905 | - | FK Pardubice | 1:2 | |
República Checa