| 5. Jornada | 28.08.2022 | FC Hradec Králové | - | Sigma Olomouc | 1:0 | ||||
| 6. Jornada | 31.08.2022 | Sigma Olomouc | - | Slovan Liberec | 1:1 | ||||
| 7. Jornada | 04.09.2022 | FK Pardubice | - | Sigma Olomouc | 0:2 | ||||
| 8. Jornada | 10.09.2022 | Sigma Olomouc | - | Viktoria Plzeň | 2:3 | ||||
| 9. Jornada | 17.09.2022 | Dynamo České Budějovice | - | Sigma Olomouc | 0:3 | ||||
| 10. Jornada | 01.10.2022 | FK Mladá Boleslav | - | Sigma Olomouc | 1:1 | ||||
| 11. Jornada | 09.10.2022 | Sigma Olomouc | - | Slavia Praga | 2:0 | ||||
| 12. Jornada | 15.10.2022 | Bohemians Praha 1905 | - | Sigma Olomouc | 1:1 | ||||
| 13. Jornada | 22.10.2022 | Sigma Olomouc | - | FC Trinity Zlín | 2:1 | ||||
| 14. Jornada | 30.10.2022 | FK Teplice | - | Sigma Olomouc | 2:1 | ||||
| 15. Jornada | 05.11.2022 | Sigma Olomouc | - | FK Jablonec | 3:0 |  |
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| 16. Jornada | 13.11.2022 | Zbrojovka Brno | - | Sigma Olomouc | 2:3 |  |
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| 17. Jornada | 28.01.2023 | Sigma Olomouc | - | Sparta Praga | 1:1 |
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