| 2. Jornada | 08.08.2021 | Platense Zacatecoluca | - | Alianza | 2:2 | ||||
| 3. Jornada | 11.08.2021 | Luis Ángel Firpo | - | Platense Zacatecoluca | 3:2 | ||||
| 5. Jornada | 22.08.2021 | FAS | - | Platense Zacatecoluca | 0:1 | ||||
| 6. Jornada | 25.08.2021 | Platense Zacatecoluca | - | Isidro Metapán | 2:1 | ||||
| 7. Jornada | 29.08.2021 | Platense Zacatecoluca | - | Atlético Marte | 0:2 | ||||
| 14. Jornada | 09.10.2021 | Platense Zacatecoluca | - | Luis Ángel Firpo | 1:3 |  |
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| 21. Jornada | 21.11.2021 | Jocoro FC | - | Platense Zacatecoluca | 1:1 |
El Salvador