| 1. Jornada | 05.02.2011 | Defensor Sporting | - | River Plate | 4:1 | ||||
| 3. Jornada | 19.02.2011 | Central Español | - | River Plate | 2:0 | ||||
| 6. Jornada | 13.03.2011 | River Plate | - | Danubio | 3:1 |  |
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| 8. Jornada | 02.04.2011 | River Plate | - | CA Cerro | 3:4 | |
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| 9. Jornada | 10.04.2011 | Liverpool | - | River Plate | 1:1 | ||||
| 10. Jornada | 16.04.2011 | River Plate | - | Nacional | 4:2 | |
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| 11. Jornada | 24.04.2011 | River Plate | - | Miramar Misiones | 2:1 | ||||
| 12. Jornada | 07.05.2011 | El Tanque Sisley | - | River Plate | 2:1 | ||||
| 7. Jornada | 15.05.2011 | Peñarol | - | River Plate | 1:4 | |
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| 13. Jornada | 22.05.2011 | River Plate | - | Montevideo Wanderers | 4:2 |  |
Uruguay