| 1. Jornada | 06.01.2019 | Lobos BUAP [Sub 17] | - | Santos Laguna [Sub 17] | 0:2 | ||||
| 2. Jornada | 13.01.2019 | Santos Laguna [Sub 17] | - | Monarcas Morelia [Sub 17] | 1:1 |  |
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| 3. Jornada | 18.01.2019 | Puebla FC [Sub 17] | - | Santos Laguna [Sub 17] | 0:2 | |
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| 4. Jornada | 27.01.2019 | Santos Laguna [Sub 17] | - | Deportivo Guadalajara [Sub 17] | 1:0 | ||||
| 5. Jornada | 02.02.2019 | UANL Tigres [Sub 17] | - | Santos Laguna [Sub 17] | 0:1 | ||||
| 6. Jornada | 10.02.2019 | Santos Laguna [Sub 17] | - | Club Tijuana [Sub 17] | 1:0 | ||||
| 7. Jornada | 16.02.2019 | Cruz Azul [Sub 17] | - | Santos Laguna [Sub 17] | 0:8 | |
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| 8. Jornada | 24.02.2019 | Santos Laguna [Sub 17] | - | Deportivo Toluca [Sub 17] | 2:1 | ||||
| 9. Jornada | 02.03.2019 | Club León [Sub 17] | - | Santos Laguna [Sub 17] | 1:0 | ||||
| 10. Jornada | 08.03.2019 | CD Veracruz [Sub 17] | - | Santos Laguna [Sub 17] | 1:0 | ||||
| 12. Jornada | 29.03.2019 | Atlas Guadalajara [Sub 17] | - | Santos Laguna [Sub 17] | 3:0 | |
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| 13. Jornada | 07.04.2019 | Santos Laguna [Sub 17] | - | CF Pachuca [Sub 17] | 3:1 | |
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| 17. Jornada | 05.05.2019 | Santos Laguna [Sub 17] | - | Pumas UNAM [Sub 17] | 1:1 |
México