| 1. Jornada | 07.02.2022 | Royal Pari | - | Jorge Wilstermann | 0:2 | ||||
| 2. Jornada | 12.02.2022 | Always Ready | - | Royal Pari | 2:2 |  |
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| 3. Jornada | 20.02.2022 | Royal Pari | - | Blooming | 1:1 | ||||
| 6. Jornada | 21.03.2022 | CD Guabirá | - | Royal Pari | 0:3 | ||||
| 8. Jornada | 09.04.2022 | Royal Pari | - | Independiente Petrolero | 5:1 | ||||
| 9. Jornada | 17.04.2022 | Jorge Wilstermann | - | Royal Pari | 2:2 | ||||
| 10. Jornada | 20.04.2022 | Royal Pari | - | Always Ready | 5:1 | ||||
| 12. Jornada | 01.05.2022 | Royal Pari | - | Real Tomayapo | 6:1 | ||||
| 13. Jornada | 07.05.2022 | Royal Pari | - | CD Guabirá | 1:3 | ||||
| 15. Jornada | 15.05.2022 | Royal Pari | - | Bolívar | 2:1 |
Bolivia