| 1. Jornada | 25.07.2010 | Universitario de Sucre | - | Club San José | 2:2 |  |
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| 9. Jornada | 12.09.2010 | Bolívar | - | Club San José | 0:0 | ||||
| 12. Jornada | 03.10.2010 | Club San José | - | Universitario de Sucre | 2:1 | ||||
| 14. Jornada | 10.10.2010 | Club San José | - | Jorge Wilstermann | 2:0 | ||||
| 16. Jornada | 24.10.2010 | Club San José | - | CD Guabirá | 5:1 | ||||
| 13. Jornada | 28.10.2010 | Blooming | - | Club San José | 2:2 | ||||
| 17. Jornada | 04.11.2010 | Real Potosí | - | Club San José | 1:3 | ||||
| 19. Jornada | 07.11.2010 | Club Aurora | - | Club San José | 4:1 |
Bolivia