| 2. Jornada | 14.01.2018 | Club León | - | Deportivo Toluca | 3:1 | ||||
| 6. Jornada | 11.02.2018 | Club León | - | Puebla FC | 2:1 | ||||
| 7. Jornada | 15.02.2018 | Santos Laguna | - | Club León | 5:1 | ||||
| 10. Jornada | 04.03.2018 | Club León | - | Pumas UNAM | 3:0 | ||||
| 11. Jornada | 11.03.2018 | CF América | - | Club León | 2:0 | ||||
| 12. Jornada | 18.03.2018 | Club León | - | Lobos BUAP | 2:2 | ||||
| 13. Jornada | 01.04.2018 | UANL Tigres | - | Club León | 4:1 | ||||
| 14. Jornada | 08.04.2018 | Club León | - | Monarcas Morelia | 2:3 | ||||
| 15. Jornada | 16.04.2018 | CD Veracruz | - | Club León | 1:2 |  |
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| 16. Jornada | 22.04.2018 | Club León | - | Club Tijuana | 1:1 | ||||
| 17. Jornada | 29.04.2018 | Deportivo Guadalajara | - | Club León | 0:2 |
México