| 1. Jornada | 08.01.2022 | Cruz Azul [Sub 18] | - | Club Tijuana [Sub 18] | 3:2 | ||||
| 2. Jornada | 15.01.2022 | Club Tijuana [Sub 18] | - | Club León [Sub 18] | 1:2 |  |
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| 11. Jornada | 18.03.2022 | Club Tijuana [Sub 18] | - | FC Juárez [Sub 18] | 3:2 | ||||
| 9. Jornada | 06.04.2022 | Club Tijuana [Sub 18] | - | Atlético San Luis [Sub 18] | 2:1 | ||||
| 14. Jornada | 15.04.2022 | Club Tijuana [Sub 18] | - | CF América [Sub 18] | 2:0 | ||||
| 16. Jornada | 24.04.2022 | Club Tijuana [Sub 18] | - | Gallos Blancos [Sub 18] | 4:1 |
México