| 6. Jornada | 13.03.2022 | Nacional Potosí | - | Real Tomayapo | 5:0 |  |
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| 8. Jornada | 10.04.2022 | Real Tomayapo | - | Blooming | 1:2 | ||||
| 10. Jornada | 20.04.2022 | Independiente Petrolero | - | Real Tomayapo | 1:1 | ||||
| 11. Jornada | 23.04.2022 | Real Tomayapo | - | Always Ready | 1:1 | ||||
| 12. Jornada | 01.05.2022 | Royal Pari | - | Real Tomayapo | 6:1 | ||||
| 13. Jornada | 07.05.2022 | Real Tomayapo | - | Nacional Potosí | 1:0 | ||||
| 16. Jornada | 22.05.2022 | Blooming | - | Real Tomayapo | 2:1 |
Bolivia