| 1. Jornada | 20.03.2021 | Club San José | - | Atlético Palmaflor | 1:3 | ||||
| 4. Jornada | 10.04.2021 | Atlético Palmaflor | - | Oriente Petrolero | 2:1 | ||||
| 6. Jornada | 03.05.2021 | Atlético Palmaflor | - | Jorge Wilstermann | 3:1 | ||||
| 8. Jornada | 11.07.2021 | Always Ready | - | Atlético Palmaflor | 3:2 | ||||
| 14. Jornada | 08.08.2021 | Club Aurora | - | Atlético Palmaflor | 2:1 | ||||
| 18. Jornada | 14.09.2021 | Atlético Palmaflor | - | Nacional Potosí | 0:0 | ||||
| 19. Jornada | 20.09.2021 | Oriente Petrolero | - | Atlético Palmaflor | 3:0 | ||||
| 20. Jornada | 23.09.2021 | Atlético Palmaflor | - | The Strongest | 0:0 |  |
Bolivia