| 1. Jornada | 20.02.2018 | Guayaquil City | - | Técnico Universitario | 0:0 |  |
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| 2. Jornada | 27.02.2018 | LDU Quito | - | Guayaquil City | 2:1 | ||||
| 3. Jornada | 06.03.2018 | Guayaquil City | - | Emelec | 0:3 | |
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| 4. Jornada | 10.03.2018 | Independiente del Valle | - | Guayaquil City | 1:1 |  |
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| 6. Jornada | 25.03.2018 | El Nacional | - | Guayaquil City | 3:1 | ||||
| 7. Jornada | 02.04.2018 | Guayaquil City | - | Aucas | 2:2 | ||||
| 8. Jornada | 10.04.2018 | Macará | - | Guayaquil City | 2:0 | ||||
| 9. Jornada | 17.04.2018 | Guayaquil City | - | Barcelona | 0:1 | |
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| 10. Jornada | 21.04.2018 | Guayaquil City | - | Universidad Catolica | 1:1 | ||||
| 11. Jornada | 28.04.2018 | Deportivo Cuenca | - | Guayaquil City | 1:1 | ||||
| 12. Jornada | 06.05.2018 | Guayaquil City | - | Deportivo Cuenca | 1:0 | ||||
| 13. Jornada | 12.05.2018 | Universidad Catolica | - | Guayaquil City | 2:1 | ||||
| 14. Jornada | 19.05.2018 | Barcelona | - | Guayaquil City | 0:2 | ||||
| 20. Jornada | 02.07.2018 | Emelec | - | Guayaquil City | 2:1 | ||||
| 21. Jornada | 07.07.2018 | Guayaquil City | - | LDU Quito | 0:0 | |
Ecuador