| 1. Jornada | 10.01.2021 | UANL Tigres | - | Club León | 2:0 | ||||
| 2. Jornada | 19.01.2021 | Club León | - | CF Pachuca | 0:0 |  |
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| 4. Jornada | 02.02.2021 | Club León | - | Atlético San Luis | 3:1 | ||||
| 5. Jornada | 09.02.2021 | Club León | - | Deportivo Guadalajara | 1:3 | ||||
| 6. Jornada | 13.02.2021 | Club Tijuana | - | Club León | 2:0 | ||||
| 7. Jornada | 21.02.2021 | Pumas UNAM | - | Club León | 0:1 | ||||
| 3. Jornada | 11.03.2021 | CF Monterrey | - | Club León | 1:1 |
México