| 9. Jornada | 05.03.2022 | Cruz Azul [Sub 16] | - | CF América [Sub 16] | 3:2 | ||||
| 10. Jornada | 12.03.2022 | CF Pachuca [Sub 16] | - | Cruz Azul [Sub 16] | 2:2 |  |
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| 15. Jornada | 23.03.2022 | Cruz Azul [Sub 16] | - | Pumas UNAM [Sub 16] | 0:2 | ||||
| 12. Jornada | 26.03.2022 | Cruz Azul [Sub 16] | - | FC Juárez [Sub 16] | 7:3 | |
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| 18. Jornada | 07.05.2022 | Cruz Azul [Sub 16] | - | Club Necaxa [Sub 16] | 2:4 | |
Venezuela
México