| 2. Jornada | 24.01.2022 | Platense | - | Real España | 2:1 | ||||
| 3. Jornada | 06.02.2022 | Platense | - | Victoria | 0:2 | ||||
| 4. Jornada | 10.02.2022 | Lobos UPNFM | - | Platense | 1:2 | ||||
| 8. Jornada | 03.03.2022 | Platense | - | Olimpia | 0:3 | ||||
| 9. Jornada | 07.03.2022 | Platense | - | Honduras Progreso | 0:0 |  |
|||
| 10. Jornada | 13.03.2022 | Victoria | - | Platense | 0:1 | ||||
| 12. Jornada | 03.04.2022 | Platense | - | Lobos UPNFM | 1:0 | ||||
| 16. Jornada | 21.04.2022 | Platense | - | Marathón | 1:0 | ||||
| 18. Jornada | 01.05.2022 | Honduras Progreso | - | Platense | 3:1 |
Honduras