| 1. Jornada | 23.07.2021 | Club Necaxa [Sub 18] | - | Santos Laguna [Sub 18] | 3:1 |  |
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| 13. Jornada | 15.10.2021 | Club Necaxa [Sub 18] | - | Puebla FC [Sub 18] | 4:3 | ||||
| 14. Jornada | 20.10.2021 | Deportivo Toluca [Sub 18] | - | Club Necaxa [Sub 18] | 2:3 | ||||
| 15. Jornada | 23.10.2021 | CF Monterrey [Sub 18] | - | Club Necaxa [Sub 18] | 1:3 | ||||
| 16. Jornada | 29.10.2021 | Club Necaxa [Sub 18] | - | Mazatlán FC [Sub 18] | 3:0 |  |
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| 17. Jornada | 06.11.2021 | Club León [Sub 18] | - | Club Necaxa [Sub 18] | 3:2 |
México