| 1. Jornada | 02.08.2020 | Real Estelí FC | - | Club Deportivo Ocotal | 2:1 |  |
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| 2. Jornada | 09.08.2020 | Chinandega | - | Real Estelí FC | 1:5 | |
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| 3. Jornada | 13.08.2020 | Real Estelí FC | - | Real Madriz | 2:0 | |
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| 4. Jornada | 16.08.2020 | Juventus Managua | - | Real Estelí FC | 1:4 | |
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| 5. Jornada | 23.08.2020 | Real Estelí FC | - | ART Municipal Jalapa | 2:1 | |
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| 6. Jornada | 30.08.2020 | CD Walter Ferretti | - | Real Estelí FC | 0:0 | ||||
| 7. Jornada | 06.09.2020 | Real Estelí FC | - | Diriangén FC | 1:0 | |
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| 8. Jornada | 13.09.2020 | Junior Managua | - | Real Estelí FC | 0:0 | ||||
| 9. Jornada | 20.09.2020 | Managua FC | - | Real Estelí FC | 3:4 | |
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| 11. Jornada | 01.10.2020 | Real Estelí FC | - | Chinandega | 3:0 | |
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| 12. Jornada | 19.10.2020 | Real Madriz | - | Real Estelí FC | 1:0 | ||||
| 13. Jornada | 24.10.2020 | Real Estelí FC | - | Juventus Managua | 3:0 | |
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| 14. Jornada | 29.10.2020 | ART Municipal Jalapa | - | Real Estelí FC | 1:0 | ||||
| 15. Jornada | 01.11.2020 | Real Estelí FC | - | CD Walter Ferretti | 1:1 | |
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| 17. Jornada | 16.11.2020 | Real Estelí FC | - | Junior Managua | 1:1 | |
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| 18. Jornada | 20.11.2020 | Real Estelí FC | - | Managua FC | 1:0 |
Nicaragua
Guatemala 